Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723167 | 0.84 | GAA (0.68) | GAAHSD17B10FGFR1HCAR3HPGD | |
| SCHEMBL30497269 | 0.83 | GAA (0.70) | GAAHSD17B10FGFR1HCAR3HPGD | |
| SCHEMBL1844583 | 0.81 | FGFR1 (0.44) | GAAHSD17B10FGFR1HPGDALDH1A1 | |
| SCHEMBL30497313 | 0.81 | GAA (0.75) | GAAHSD17B10FGFR1HCAR3HPGD | |
| SCHEMBL29779897 | 0.81 | GAA (0.56) | GAAHSD17B10FGFR1HCAR3HPGD | |
| SCHEMBL23361781 | 0.78 | FGFR1 (0.47) | GAAHSD17B10FGFR1TBXA2R | |
| SCHEMBL29393184 | 0.78 | FGFR1 (0.47) | GAAHSD17B10FGFR1TBXA2R | |
| SCHEMBL20268541 | 0.78 | FGFR1 (0.47) | GAAHSD17B10FGFR1TBXA2R | |
| SCHEMBL30548170 | 0.78 | FGFR1 (0.47) | GAAHSD17B10FGFR1TBXA2R | |
| Ammonia Solution, Strong SCHEMBL30676125 | 0.77 | FGFR1 (0.46) | GAAHSD17B10FGFR1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585249-A | Process and intermediates for preparing 2- [ (4- {6- [ (4-cyano-2-fluorobenzyl) oxy ] pyridin-2-yl } piperidin-1-yl) methyl ] -1- [ (2S) -oxetan-2-ylmethyl ] -1H-benzimidazole-6-carboxylic acid, 1, 3-dihydroxy-2- (hydroxymethyl) propan-2-amine salt | 辉瑞公司 | 2025-03-07 | — | — | CN | disclosed |