Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 17/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.50 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433539 | 1.00 | DDB1 (0.50) | DDB1CRBNIKZF2POLB | |
| SCHEMBL31433702 | 0.90 | DDB1 (0.48) | DDB1CRBNIKZF2POLB | |
| SCHEMBL31434047 | 0.90 | DDB1 (0.48) | DDB1CRBNIKZF2POLB | |
| SCHEMBL26924404 | 0.89 | DDB1 (0.60) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL31434024 | 0.88 | DDB1 (0.59) | DDB1CRBNPOLB | |
| Hydrochloric Acid SCHEMBL31433949 | 0.88 | DDB1 (0.59) | DDB1CRBNPOLB | |
| SCHEMBL31433666 | 0.86 | DDB1 (0.44) | DDB1CRBNIKZF2POLB | |
| SCHEMBL31433860 | 0.86 | DDB1 (0.44) | DDB1CRBNIKZF2POLB | |
| SCHEMBL26924652 | 0.84 | DDB1 (0.51) | DDB1CRBNIKZF2 | |
| SCHEMBL31433930 | 0.83 | DDB1 (0.51) | DDB1CRBNIKZF2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |