Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434076 | 1.00 | HPGD (0.47) | HPGDRECQLEPHX1MAPTMEN1 | |
| SCHEMBL19890506 | 1.00 | HPGD (0.47) | HPGDRECQLEPHX1MAPTMEN1 | |
| SCHEMBL19889963 | 1.00 | HPGD (0.47) | HPGDRECQLEPHX1MAPTMEN1 | |
| SCHEMBL31434084 | 1.00 | HPGD (0.47) | HPGDRECQLEPHX1MAPTMEN1 | |
| SCHEMBL1536087 | 0.88 | HPGD (0.47) | HPGDRECQLEPHX1MAPTMEN1 | |
| SCHEMBL19385409 | 0.85 | NR1H2 (0.47) | HPGDRECQLEPHX1MAPTMEN1 | |
| SCHEMBL10054588 | 0.85 | NR1H2 (0.47) | HPGDRECQLEPHX1MAPTMEN1 | |
| SCHEMBL13438476 | 0.85 | NR1H2 (0.47) | HPGDRECQLEPHX1MAPTMEN1 | |
| SCHEMBL22874296 | 0.85 | NR1H2 (0.47) | HPGDRECQLEPHX1MAPTMEN1 | |
| SCHEMBL31434109 | 0.85 | HPGD (0.48) | HPGDRECQLEPHX1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |