Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 5/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23538393 | 0.92 | DDB1 (0.53) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL23538562 | 0.90 | DDB1 (0.55) | DDB1CRBNNAMPTJAK1P2RY14 | |
| SCHEMBL29946867 | 0.90 | DDB1 (0.54) | DDB1CRBNNAMPTJAK1P2RY14 | |
| SCHEMBL30738778 | 0.86 | DDB1 (0.50) | DDB1CRBNNAMPTJAK1KDM4E | |
| SCHEMBL27179051 | 0.86 | DDB1 (0.50) | DDB1CRBNNAMPTJAK1KDM4E | |
| SCHEMBL29279129 | 0.86 | DDB1 (0.53) | DDB1CRBNCDK12KDM4EMAPT | |
| SCHEMBL29279158 | 0.86 | DDB1 (0.53) | DDB1CRBNCDK12KDM4EMAPT | |
| SCHEMBL29977165 | 0.86 | DDB1 (0.53) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL29279138 | 0.86 | DDB1 (0.53) | DDB1CRBNCDK12KDM4EMAPT | |
| SCHEMBL30703654 | 0.84 | DDB1 (0.48) | DDB1CRBNNAMPTJAK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |