Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.74 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 4/20 | 0.51 |
| ▸ | RET | P07949 | 3/20 | 0.51 |
| ▸ | FLT3 | P36888 | 3/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.51 |
| ▸ | PLK4 | O00444 | 2/20 | 0.51 |
| ▸ | PLK1 | P53350 | 2/20 | 0.51 |
| ▸ | JAK3 | P52333 | 2/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.51 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20838 | 0.85 | RPS6KA3 (1.00) | RPS6KA3DYRK1AMEN1ALDH1A1LMNA | |
| SCHEMBL20839 | 0.85 | RPS6KA3 (1.00) | RPS6KA3DYRK1AMEN1ALDH1A1LMNA | |
| SCHEMBL905690 | 0.85 | RPS6KA3 (1.00) | RPS6KA3DYRK1AMEN1ALDH1A1LMNA | |
| SCHEMBL1305325 | 0.80 | POLB (0.80) | RPS6KA3DYRK1AMEN1ALDH1A1LMNA | |
| SCHEMBL1305323 | 0.80 | POLB (0.80) | RPS6KA3DYRK1AMEN1ALDH1A1LMNA | |
| SCHEMBL6001158 | 0.78 | RPS6KA3 (0.63) | RPS6KA3DYRK1AMEN1ALDH1A1LMNA | |
| SCHEMBL6001160 | 0.78 | RPS6KA3 (0.63) | RPS6KA3DYRK1AMEN1ALDH1A1LMNA | |
| SCHEMBL14448922 | 0.74 | RPS6KA3 (0.62) | RPS6KA3DYRK1AMEN1ALDH1A1LMNA | |
| SCHEMBL701968 | 0.73 | POLB (0.70) | RPS6KA3DYRK1AMEN1ALDH1A1LMNA | |
| SCHEMBL6001779 | 0.73 | POLB (0.70) | RPS6KA3DYRK1AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085819-A1 | KINASE INHIBITOR COMPOSITIONS AND RELATED METHODS FOR THE TREATMENT OF A DISEASE | WASHINGTON UNIVERSITY (US) | 2025-04-24 | — | — | WO | disclosed |