Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | HTT | P42858 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | ALPL | P05186 | 1/20 | 0.61 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5298396 | 1.00 | KDM4E (0.66) | KDM4EHTTSMN1; SMN2MAPTALPL | |
| SCHEMBL1147702 | 0.87 | KDM4E (0.73) | KDM4EHTTSMN1; SMN2MAPTTLR7 | |
| SCHEMBL24932399 | 0.85 | KDM4E (0.64) | KDM4EHTTSMN1; SMN2MAPTALPL | |
| SCHEMBL24931247 | 0.82 | KDM4E (0.69) | KDM4EHTTSMN1; SMN2MAPTALPL | |
| SCHEMBL14810907 | 0.80 | KDM4E (0.67) | KDM4EHTTSMN1; SMN2MAPTALPL | |
| SCHEMBL24931101 | 0.79 | TLR7 (0.78) | KDM4EHTTSMN1; SMN2MAPTTLR7 | |
| Azapicyl SCHEMBL24931095 | 0.79 | KDM4E (0.68) | KDM4EHTTSMN1; SMN2MAPTALPL | |
| SCHEMBL1314391 | 0.79 | KDM4E (0.68) | KDM4EHTTSMN1; SMN2MAPTALPL | |
| SCHEMBL24931082 | 0.79 | KDM4E (0.69) | KDM4EHTTSMN1; SMN2MAPTALPL | |
| SCHEMBL9341104 | 0.78 | KMT2A (0.83) | SMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |