Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25409660 | 1.00 | CYP2C19 (0.45) | CYP2C19POLBMEN1KMT2ARAB9A | |
| SCHEMBL23861174 | 0.82 | PDGFRB (0.56) | CYP2C19POLBMEN1KMT2ARAB9A | |
| SCHEMBL30443482 | 0.82 | PDGFRB (0.56) | CYP2C19POLBMEN1KMT2ARAB9A | |
| SCHEMBL31232927 | 0.81 | CYP1A2 (0.55) | POLBMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL25410628 | 0.81 | CYP1A2 (0.55) | POLBMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL25407643 | 0.80 | MEN1 (0.46) | MEN1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL31232898 | 0.80 | KMT2A (0.41) | CYP2C19POLBMEN1KMT2ARAB9A | |
| SCHEMBL30599924 | 0.80 | MEN1 (0.46) | MEN1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL25408884 | 0.80 | KMT2A (0.41) | CYP2C19POLBMEN1KMT2ARAB9A | |
| SCHEMBL17006473 | 0.79 | SETDB1 (0.51) | CYP2C19POLBMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301127-A | 6-Oxo-decahydro pyrrolo [1,2-a ] [1,5] diazocine and 6-oxo-decahydro-4H-pyrrolo [2,1-d ] [1,5] thiaazacine derivatives as modulators of STAT3 and STAT6 for the treatment of cancer and inflammatory conditions | 瑞克鲁迪克斯制药股份有限公司 | 2025-01-10 | — | — | CN | disclosed |