Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31436240 | 1.00 | NR1H2 (0.40) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL692003 | 0.87 | NR1H2 (0.41) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL27752938 | 0.87 | NR1H2 (0.41) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL17062766 | 0.86 | NR1H2 (0.42) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL656518 | 0.85 | NR1H2 (0.40) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6628364 | 0.85 | NR1H2 (0.40) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL17062858 | 0.85 | NR1H2 (0.40) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL336866 | 0.84 | NR1H2 (0.50) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL18683 | 0.84 | NR1H2 (0.43) | NR1H2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL1462710 | 0.84 | NR1H2 (0.50) | NR1H2MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743459-A1 | BICYCLIC AND MONOCYCLIC TRPA1 INHIBITORS | D.E. Shaw Research, LLC (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025014922-A1 | BICYCLIC AND MONOCYCLIC TRPA1 INHIBITORS | D. E. SHAW RESEARCH, LLC (US) | 2025-01-16 | — | — | WO | disclosed |