Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 13/20 | 0.71 |
| ▸ | EML4 | Q9HC35 | 11/20 | 0.71 |
| ▸ | ALK | Q9UM73 | 11/20 | 0.71 |
| ▸ | RET | P07949 | 11/20 | 0.71 |
| ▸ | ROS1 | P08922 | 11/20 | 0.71 |
| ▸ | AXL | P30530 | 3/20 | 0.71 |
| ▸ | ETV6 | P41212 | 3/20 | 0.71 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.71 |
| ▸ | PLK4 | O00444 | 1/20 | 0.71 |
| ▸ | CIT | O14578 | 1/20 | 0.71 |
| ▸ | AURKA | O14965 | 1/20 | 0.71 |
| ▸ | GAK | O14976 | 1/20 | 0.71 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.71 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.71 |
| ▸ | BUB1 | O43683 | 1/20 | 0.71 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.71 |
| ▸ | STK16 | O75716 | 1/20 | 0.71 |
| ▸ | STK10 | O94804 | 1/20 | 0.71 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.71 |
| ▸ | LATS1 | O95835 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31436351 | 0.98 | FLT3 (0.71) | FLT3EML4ALKRETROS1 | |
| SCHEMBL31436399 | 0.98 | FLT3 (0.71) | FLT3EML4ALKRETROS1 | |
| SCHEMBL31436371 | 0.98 | FLT3 (0.71) | FLT3EML4ALKRETROS1 | |
| SCHEMBL31436348 | 0.98 | FLT3 (0.71) | FLT3EML4ALKRETROS1 | |
| SCHEMBL31436388 | 0.96 | FLT3 (0.73) | FLT3EML4ALKRETROS1 | |
| SCHEMBL31436396 | 0.93 | FLT3 (0.80) | FLT3EML4ALKRETROS1 | |
| SCHEMBL31436389 | 0.92 | FLT3 (0.69) | FLT3EML4ALKRETROS1 | |
| SCHEMBL31436377 | 0.92 | FLT3 (0.69) | FLT3EML4ALKRETROS1 | |
| SCHEMBL10156928 | 0.89 | FLT3 (0.89) | FLT3EML4ALKRETROS1 | |
| SCHEMBL21455129 | 0.88 | FLT3 (0.82) | FLT3EML4ALKRETROS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306708-A | FLT3-HDAC double-target inhibitor and preparation method and application thereof | 山东大学 | 2025-01-14 | — | — | CN | claimed |
| CN-119306708-A | FLT3-HDAC double-target inhibitor and preparation method and application thereof | 山东大学 | 2025-01-14 | — | — | CN | disclosed |