Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | IL1B | P01584 | 3/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31436460 | 0.88 | AR (0.34) | ARLRRK2 | |
| SCHEMBL31349577 | 0.85 | AR (0.39) | ARIL1B | |
| SCHEMBL31436493 | 0.82 | AR (0.31) | AR | |
| SCHEMBL31436537 | 0.81 | AR (0.31) | AR | |
| SCHEMBL31436484 | 0.81 | AR (0.46) | ARIL1B | |
| SCHEMBL25313086 | 0.74 | AR (0.40) | ARIL1BLRRK2 | |
| SCHEMBL30507063 | 0.74 | AR (0.40) | ARIL1BLRRK2 | |
| SCHEMBL30507049 | 0.74 | AR (0.40) | ARIL1B | |
| SCHEMBL25316359 | 0.74 | AR (0.40) | ARIL1B | |
| SCHEMBL25924822 | 0.74 | AR (0.40) | ARIL1BLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743079-A2 | APOL1 INHIBITORS AND METHODS OF USE THEREOF | Maze Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015106-A2 | APOL1 INHIBITORS AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |