Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK2 | P51955 | 2/20 | 0.57 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23791804 | 1.00 | NEK2 (0.57) | NEK2CHEK2CHEK1MAPTKDM4E | |
| SCHEMBL25544946 | 0.85 | NR4A2 (0.50) | NEK2CHEK2CHEK1MAPTKDM4E | |
| SCHEMBL25545582 | 0.84 | KMT2A (0.49) | NEK2CHEK2CHEK1MAPTKDM4E | |
| SCHEMBL30295565 | 0.84 | KMT2A (0.49) | NEK2CHEK2CHEK1MAPTKDM4E | |
| SCHEMBL23782395 | 0.83 | CHEK1 (0.59) | NEK2CHEK2CHEK1KDM4ENPC1 | |
| SCHEMBL31437812 | 0.82 | NEK2 (0.45) | NEK2CHEK2CHEK1MAPTKDM4E | |
| SCHEMBL21798966 | 0.80 | HDAC1 (0.59) | MAPTKDM4ENPC1NR4A2HDAC1 | |
| SCHEMBL3713695 | 0.79 | AXL (0.59) | CHEK2MAPTKMT2AMEN1IKBKE | |
| SCHEMBL25546300 | 0.77 | MAPT (0.51) | NEK2CHEK2CHEK1MAPTKDM4E | |
| SCHEMBL13363241 | 0.77 | NR4A2 (0.58) | MAPTKDM4ENPC1NR4A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011533-A1 | CARBOXYLIC ACID COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海宇道生物技术有限公司 | 2025-01-16 | — | — | WO | disclosed |