Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31439265 | 1.00 | ABCC1 (0.50) | ABCC1CA12CA1CA2CA9 | |
| SCHEMBL9014154 | 0.77 | ABCC1 (0.51) | ABCC1CA12CA1CA2CA9 | |
| SCHEMBL8649331 | 0.75 | ABCC1 (0.50) | ABCC1CA12CA1CA2CA9 | |
| SCHEMBL31188779 | 0.75 | ABCC1 (0.50) | ABCC1CA12CA1CA2CA9 | |
| SCHEMBL14721896 | 0.73 | ABCC1 (0.49) | ABCC1CA12CA1CA2CA9 | |
| SCHEMBL7082013 | 0.71 | ABCC1 (0.50) | ABCC1CA12CA1CA2CA9 | |
| SCHEMBL28829514 | 0.71 | ABCC1 (0.46) | ABCC1CA12CA1CA2CA9 | |
| SCHEMBL29025727 | 0.69 | ABCC1 (0.45) | ABCC1CA12CA1CA2CA9 | |
| SCHEMBL19610634 | 0.69 | ABCC1 (0.41) | ABCC1CA12CA1CA2CA9 | |
| SCHEMBL19610645 | 0.67 | ABCC1 (0.43) | ABCC1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661513-A | NO donor type dasatinib derivative and preparation method and application thereof | 中山大学中山眼科中心 | 2025-03-21 | — | — | CN | disclosed |