Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478976 | 0.87 | NPC1 (0.36) | KMT2ARAB9AMEN1NPC1SLC6A3 | |
| SCHEMBL13980917 | 0.82 | CNR1 (0.43) | KMT2ARAB9AMEN1NPC1RECQL | |
| SCHEMBL13478938 | 0.81 | CNR1 (0.43) | KMT2ARAB9AMEN1NPC1RECQL | |
| SCHEMBL3146828 | 0.81 | CNR1 (0.43) | KMT2ARAB9AMEN1NPC1RECQL | |
| SCHEMBL13478984 | 0.80 | CNR1 (0.32) | KMT2AMEN1SLC6A3CNR1CNR2 | |
| SCHEMBL13478948 | 0.79 | CNR1 (0.40) | KMT2ARAB9AMEN1NPC1RECQL | |
| SCHEMBL13478950 | 0.79 | CNR1 (0.32) | SLC6A3CNR1CNR2 | |
| SCHEMBL4658459 | 0.77 | KMT2A (0.36) | KMT2ARAB9AMEN1NPC1RECQL | |
| SCHEMBL2448618 | 0.77 | IRAK4 (0.43) | — | |
| SCHEMBL12903702 | 0.77 | HTT (0.51) | KMT2ARAB9ANPC1RECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558592-B1 | THIAZOL-(BI)CYCLOALKYL-CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-02-17 | — | — | EP | disclosed |
| EP-1558592-B1 | THIAZOL-(BI)CYCLOALKYL-CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-02-17 | — | — | EP | disclosed |
| US-7470793-B2 | Thiazol-(bi)cycloalkyl-carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-12-30 | — | — | US | disclosed |
| US-7470793-B2 | Thiazol-(bi)cycloalkyl-carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-12-30 | — | — | US | disclosed |
| US-7470793-B2 | Thiazol-(bi)cycloalkyl-carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-12-30 | — | — | US | disclosed |
| US-20060155122-A1 | Thiazol-(bi)cycloalkyl-carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2006-07-13 | — | — | US | disclosed |
| EP-1558592-A1 | THIAZOL-(BI)CYCLOALKYL-CARBOXANILIDES | Bayer CropScience Aktiengesellschaft (DE) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004039789-A1 | THIAZOL-(BI)CYCLOALKYL-CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060155122-A1 | Thiazol-(bi)cycloalkyl-carboxanilides | MRPL21, Q6ZSR9, QPCT | KMT2A 3021/4885RAB9A 1532/4885MEN1 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.