SCHEMBL31440574

SCHEMBL31440574

Cc1ccc(Oc2cc(Br)cc(C(C)(C)O)c2)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.40
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
TLR8 Q9NR97 1/20 0.37
SLC6A4 P31645 4/20 0.36
HTR2A P28223 3/20 0.36
KCNH2 Q12809 3/20 0.36
CHEK2 O96017 1/20 0.34
ICAM1 P05362 1/20 0.33
SELE P16581 1/20 0.33
LMNA P02545 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CDK8 P49336 1/20 0.32
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
CYP3A4 P08684 1/20 0.31
MMP9 P14780 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31440580 1.00 HSP90AA1 (0.40) HSP90AA1NR1H2NR1H3TLR8SLC6A4
SCHEMBL31440612 0.75 NR1H2 (0.34) HSP90AA1NR1H2NR1H3SLC6A4HTR2A
SCHEMBL14396803 0.74 HTR2A (0.51) HSP90AA1SLC6A4HTR2AKCNH2CHEK2
SCHEMBL31440620 0.73 NOTUM (0.43) NR1H2NR1H3SLC6A4HTR2AKCNH2
SCHEMBL14649911 0.72 HTR2A (0.44) HSP90AA1SLC6A4HTR2AKCNH2CHEK2
SCHEMBL14396805 0.72 HTR2A (0.44) HSP90AA1SLC6A4HTR2AKCNH2CHEK2
SCHEMBL31440599 0.71 BRD4 (0.35) KCNH2
SCHEMBL309871 0.71 CA1 (0.41) LMNACYP3A4MEN1KMT2A
SCHEMBL23087844 0.71 PRMT5 (0.44) SLC6A4HTR2AKCNH2CHEK2ICAM1
SCHEMBL14649910 0.69 HSP90AA1 (0.57) HSP90AA1SLC6A4HTR2AKCNH2DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025014200-A1 COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 티움바이오 2025-01-16 WO disclosed