Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31440592 | 0.89 | NPC1 (0.41) | NPC1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL31440647 | 0.89 | NPC1 (0.40) | NPC1MAPTKLKB1ALDH1A1 | |
| SCHEMBL31440613 | 0.88 | NPC1 (0.46) | NPC1BRD4KDM4EMAPTKLKB1 | |
| SCHEMBL23233778 | 0.88 | NPC1 (0.38) | NPC1BRD4SMN1; SMN2GAAPOLB | |
| SCHEMBL20535691 | 0.82 | NPC1 (0.35) | NPC1SMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL31440547 | 0.81 | NPC1 (0.39) | NPC1MAPT | |
| SCHEMBL23233774 | 0.80 | BRD4 (0.40) | NPC1BRD4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31651632 | 0.79 | MAPT (0.35) | NPC1SMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL31440587 | 0.79 | NPC1 (0.36) | NPC1 | |
| SCHEMBL31440604 | 0.78 | NPC1 (0.36) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025014200-A1 | COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 티움바이오 | 2025-01-16 | — | — | WO | disclosed |