Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.39 |
| ▸ | CDK2 | P24941 | 7/20 | 0.38 |
| ▸ | BRAF | P15056 | 6/20 | 0.38 |
| ▸ | CDK1 | P06493 | 6/20 | 0.38 |
| ▸ | CDK4 | P11802 | 5/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | CDK16 | Q00536 | 2/20 | 0.38 |
| ▸ | CDK17 | Q00537 | 2/20 | 0.38 |
| ▸ | DSTYK | Q6XUX3 | 2/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31443365 | 0.89 | BRAF (0.51) | IKBKBCDK2BRAFCDK1CDK4 | |
| SCHEMBL31443311 | 0.76 | BRAF (0.49) | IKBKBCDK2BRAFCDK1CDK4 | |
| SCHEMBL31443445 | 0.76 | BRAF (0.58) | IKBKBCDK2BRAFCDK1CDK4 | |
| SCHEMBL2193137 | 0.75 | BRAF (0.66) | IKBKBCDK2BRAFCDK1CDK4 | |
| SCHEMBL31443337 | 0.75 | IKBKB (0.48) | IKBKBCDK2BRAFCDK1CDK4 | |
| SCHEMBL31443342 | 0.73 | BRAF (0.60) | IKBKBCDK2BRAFCDK1CDK4 | |
| SCHEMBL31443369 | 0.73 | BRAF (0.63) | IKBKBCDK2BRAFCDK1CDK4 | |
| SCHEMBL31443292 | 0.72 | BRAF (0.58) | IKBKBCDK2BRAFCDK1CDK4 | |
| SCHEMBL31443324 | 0.72 | BRAF (0.59) | CDK2BRAFCDK1CDK4CDK6 | |
| SCHEMBL12350384 | 0.71 | NR1I2 (0.58) | IKBKBCDK2BRAFCDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072462-A1 | SULFONAMIDE DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |