Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 11/20 | 0.48 |
| ▸ | GRM5 | P41594 | 10/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31192678 | 0.92 | PDK4 (0.55) | PDK4HTR6JAK1GRM1GRM5 | |
| SCHEMBL15545634 | 0.88 | PDK4 (0.54) | PDK4HTR6JAK1GRM1GRM5 | |
| SCHEMBL30112465 | 0.88 | PDK4 (0.54) | PDK4HTR6JAK1GRM1GRM5 | |
| SCHEMBL1199843 | 0.88 | PDK4 (0.54) | PDK4HTR6JAK1GRM1GRM5 | |
| SCHEMBL31222963 | 0.88 | PDK4 (0.54) | PDK4HTR6JAK1GRM1GRM5 | |
| SCHEMBL31443630 | 0.88 | PDK4 (0.54) | PDK4HTR6JAK1GRM1GRM5 | |
| SCHEMBL12713080 | 0.88 | PDK4 (0.58) | PDK4HTR6JAK1GRM1GRM5 | |
| SCHEMBL31223106 | 0.87 | PDK4 (0.53) | PDK4HTR6JAK1GRM1GRM5 | |
| SCHEMBL31223062 | 0.87 | PDK4 (0.53) | PDK4HTR6JAK1GRM1GRM5 | |
| SCHEMBL6629675 | 0.86 | PDK4 (0.53) | PDK4HTR6JAK1GRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096856-A1 | COVALENT CEREBLON LIGANDS | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |