SCHEMBL31443596

SCHEMBL31443596

CC(C)(C)OC(=O)N1CCC(c2ccc(OC3CCC(=O)NC3=O)cc2O)CC1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 18/20 0.53
▸ CRBN Q96SW2 18/20 0.53
▸ KDM4E B2RXH2 1/20 0.45
▸ MAPT P10636 1/20 0.45
▸ THRB P10828 1/20 0.45
▸ HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444271 0.90 DDB1 (0.50) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31444225 0.88 DDB1 (0.49) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31444151 0.87 DDB1 (0.48) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31323424 0.86 DDB1 (0.56) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL24125697 0.85 DDB1 (0.62) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL24125822 0.85 DDB1 (0.62) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL23301516 0.85 DDB1 (0.62) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31444036 0.85 DDB1 (0.48) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31443702 0.83 DDB1 (0.64) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL24125934 0.81 DDB1 (0.58) DDB1CRBNKDM4EMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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