SCHEMBL31443740

SCHEMBL31443740

O=C1CCC(n2cnc(-c3cccc(S(=O)(=O)F)c3)c2)C(=O)N1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 19/20 0.50
▸ DDB1 Q16531 11/20 0.44
▸ IKZF3 Q9UKT9 4/20 0.44
▸ ALDH1A1 P00352 1/20 0.38
▸ CHRM2 P08172 1/20 0.38
▸ OPRM1 P35372 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443932 0.85 CRBN (0.50) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL19586499 0.83 CRBN (0.52) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31444020 0.82 CRBN (0.46) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31443727 0.82 CRBN (0.47) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31443787 0.81 CRBN (0.50) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31444102 0.77 CRBN (0.42) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31444023 0.67 CRBN (0.69) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31443762 0.65 CRBN (0.77) CRBNDDB1
SCHEMBL31444027 0.65 CRBN (0.58) CRBNDDB1
SCHEMBL31443700 0.65 CRBN (0.77) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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