SCHEMBL31443955

SCHEMBL31443955

O=C1CCC(c2ccc(N3CCNCC3)c(S(=O)(=O)F)c2)C(=O)N1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 18/20 0.47
▸ DDB1 Q16531 15/20 0.47
▸ POLB P06746 1/20 0.39
▸ HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443569 0.84 CRBN (0.45) CRBNDDB1POLB
SCHEMBL25029440 0.84 CRBN (0.51) CRBNDDB1POLB
SCHEMBL26641504 0.82 CRBN (0.52) CRBNDDB1POLB
SCHEMBL30883516 0.82 CRBN (0.52) CRBNDDB1POLB
SCHEMBL30883502 0.81 CRBN (0.51) CRBNDDB1POLB
SCHEMBL27225354 0.81 CRBN (0.51) CRBNDDB1POLB
SCHEMBL31444160 0.81 DDB1 (0.61) CRBNDDB1
SCHEMBL31444189 0.80 CRBN (0.49) CRBNDDB1POLBHTR6
SCHEMBL30955798 0.79 CRBN (0.53) CRBNDDB1POLBHTR6
SCHEMBL21876580 0.76 CRBN (0.62) CRBNDDB1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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