SCHEMBL31444032

SCHEMBL31444032

O=C1CCC(n2cnc3cc(OS(=O)(=O)F)c(Br)cc32)C(=O)N1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 20/20 0.55
▸ DDB1 Q16531 14/20 0.55
▸ IKZF3 Q9UKT9 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443954 0.81 CRBN (0.64) CRBNDDB1IKZF3
SCHEMBL31444203 0.76 CRBN (0.43) CRBNDDB1IKZF3
SCHEMBL27241621 0.76 CRBN (0.73) CRBNDDB1IKZF3
SCHEMBL31443849 0.76 CRBN (0.41) CRBNDDB1IKZF3
SCHEMBL31443996 0.75 CRBN (0.55) CRBNDDB1IKZF3
SCHEMBL31444101 0.75 CRBN (0.55) CRBNDDB1IKZF3
SCHEMBL31444102 0.74 CRBN (0.42) CRBNDDB1IKZF3
SCHEMBL27241555 0.74 CRBN (0.73) CRBNDDB1IKZF3
SCHEMBL30819832 0.74 CRBN (0.73) CRBNDDB1IKZF3
SCHEMBL25653901 0.74 CRBN (0.73) CRBNDDB1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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