SCHEMBL31444047

SCHEMBL31444047

Nc1ccc(-c2ccn(C3CCC(=O)NC3=O)n2)cc1OS(=O)(=O)F

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 20/20 0.42
▸ DDB1 Q16531 11/20 0.36
▸ IKZF3 Q9UKT9 4/20 0.36
▸ TNF P01375 2/20 0.35
▸ IL1B P01584 2/20 0.35
▸ IKZF1 Q13422 2/20 0.35
▸ TBXA2R P21731 1/20 0.35
▸ BRD4 O60885 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443845 0.89 CRBN (0.42) CRBNDDB1IKZF3
SCHEMBL31443758 0.82 CRBN (0.50) CRBNDDB1IKZF3
SCHEMBL31443787 0.77 CRBN (0.50) CRBNDDB1IKZF3
SCHEMBL20812175 0.73 CRBN (0.51) CRBNDDB1IKZF3
SCHEMBL31443627 0.72 CRBN (0.46) CRBNDDB1IKZF3
SCHEMBL31443842 0.72 CRBN (0.46) CRBNDDB1IKZF3
SCHEMBL31444102 0.71 CRBN (0.42) CRBNDDB1IKZF3
SCHEMBL31444217 0.70 CRBN (0.46) CRBNDDB1IKZF3TNFIL1B
SCHEMBL31444088 0.67 CRBN (0.44) CRBNDDB1IKZF3TNFIL1B
SCHEMBL31443935 0.67 CRBN (0.46) CRBNDDB1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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