SCHEMBL31444119

SCHEMBL31444119

O=C1CCC(Oc2ccc(C3CCNCC3)c(OS(=O)(=O)F)c2)C(=O)N1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 16/20 0.50
▸ DDB1 Q16531 15/20 0.50
▸ SLC6A2 P23975 3/20 0.37
▸ SLC6A4 P31645 3/20 0.37
▸ SLC6A3 Q01959 3/20 0.37
▸ HTR6 P50406 1/20 0.36
▸ HTR1A P08908 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443983 0.90 DDB1 (0.55) CRBNDDB1SLC6A2SLC6A4SLC6A3
SCHEMBL31444182 0.85 CRBN (0.52) CRBNDDB1HTR6
SCHEMBL29976526 0.82 CRBN (0.55) CRBNDDB1SLC6A2SLC6A4SLC6A3
SCHEMBL27168045 0.82 CRBN (0.55) CRBNDDB1SLC6A2SLC6A4SLC6A3
SCHEMBL31443705 0.82 CRBN (0.43) CRBNDDB1
SCHEMBL31444123 0.81 CRBN (0.55) CRBNDDB1
SCHEMBL31444188 0.81 CRBN (0.55) CRBNDDB1
SCHEMBL31443868 0.81 CRBN (0.46) CRBNDDB1HTR6
SCHEMBL31444037 0.81 CRBN (0.46) CRBNDDB1HTR6
SCHEMBL31443721 0.81 CRBN (0.57) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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