SCHEMBL31444222

SCHEMBL31444222

CC(C)(C)OC(=O)N1CCC(c2ccc(C3CCC(=O)NC3=O)cc2S(=O)(=O)F)CC1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 12/20 0.60
▸ CRBN Q96SW2 12/20 0.60
▸ KDM4E B2RXH2 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ THRB P10828 1/20 0.44
▸ GPR119 Q8TDV5 4/20 0.42
▸ STS P08842 1/20 0.40
▸ NAMPT P43490 1/20 0.39
▸ SCN9A Q15858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29877042 0.88 DDB1 (0.63) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL24881088 0.88 DDB1 (0.63) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31443702 0.87 DDB1 (0.64) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31444160 0.86 DDB1 (0.61) DDB1CRBN
SCHEMBL31630961 0.86 DDB1 (0.63) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31443781 0.86 DDB1 (0.63) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31443761 0.86 DDB1 (0.58) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL30631026 0.85 DDB1 (0.66) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL26633417 0.85 DDB1 (0.66) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL26633409 0.85 DDB1 (0.66) DDB1CRBNKDM4EMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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