SCHEMBL31444244

SCHEMBL31444244

CC(C)(C)OC(=O)N1CCC(c2ccc(NC3CCC(=O)NC3=O)cc2Br)CC1

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 16/20 0.62
▸ CRBN Q96SW2 16/20 0.62
▸ MAPT P10636 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ THRB P10828 1/20 0.44
▸ ALDH1A1 P00352 2/20 0.43
▸ NPC1 O15118 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443811 0.90 DDB1 (0.63) DDB1CRBNMAPTKDM4ETHRB
SCHEMBL29744807 0.90 DDB1 (0.63) DDB1CRBNMAPTKDM4ETHRB
SCHEMBL23538523 0.90 DDB1 (0.63) DDB1CRBNMAPTKDM4ETHRB
SCHEMBL23538572 0.89 DDB1 (0.62) DDB1CRBNMAPTKDM4ETHRB
SCHEMBL23538718 0.89 DDB1 (0.62) DDB1CRBNMAPTKDM4ETHRB
SCHEMBL29946902 0.89 DDB1 (0.62) DDB1CRBNMAPTKDM4ETHRB
SCHEMBL25229938 0.89 DDB1 (0.62) DDB1CRBNMAPTKDM4ETHRB
SCHEMBL23539198 0.89 DDB1 (0.62) DDB1CRBNMAPTKDM4ETHRB
SCHEMBL29946886 0.89 DDB1 (0.62) DDB1CRBNMAPTKDM4ETHRB
SCHEMBL29535240 0.89 DDB1 (0.62) DDB1CRBNMAPTKDM4ETHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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