Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 10/20 | 0.47 |
| ▸ | CA1 | P00915 | 9/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29631628 | 0.84 | LRRK2 (0.48) | LRRK2PTK2TRPV1 | |
| SCHEMBL5567494 | 0.82 | CDK1 (0.58) | CA2CA1CA9CDK1AURKA | |
| SCHEMBL31121916 | 0.76 | CCNE1 (0.46) | LRRK2CDK1 | |
| SCHEMBL9275713 | 0.75 | CNR2 (0.40) | LRRK2PTK2TRPV1 | |
| SCHEMBL30291146 | 0.74 | JAK2 (0.49) | LRRK2CDK1 | |
| SCHEMBL30291355 | 0.74 | CCNE1 (0.55) | LRRK2CDK1 | |
| SCHEMBL30291345 | 0.74 | LRRK2 (0.51) | LRRK2CDK1 | |
| SCHEMBL30291237 | 0.74 | CCNE1 (0.44) | LRRK2CA2CA1CDK1PTK2 | |
| SCHEMBL30291198 | 0.74 | JAK2 (0.49) | LRRK2CDK1 | |
| SCHEMBL30291140 | 0.74 | JAK2 (0.49) | LRRK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532473-A1 | AMINOHETEROARYL KINASE INHIBITORS | Allorion Therapeutics Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-119343333-A | Amino heteroaryl kinase inhibitors | 安锐生物医药公司 | 2025-01-21 | — | — | CN | disclosed |