Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26147436 | 0.84 | NPC1 (0.60) | KCNA5POLBMAPK1ATMMEN1 | |
| SCHEMBL6190137 | 0.83 | KCNA5 (0.44) | KCNA5POLBMAPK1ATMMEN1 | |
| SCHEMBL6189254 | 0.83 | KCNA5 (0.41) | KCNA5POLBMAPK1ATMMEN1 | |
| SCHEMBL12743180 | 0.81 | KCNA5 (0.55) | KCNA5ATMKDM4AHDAC10HDAC6 | |
| SCHEMBL17018542 | 0.81 | KCNA5 (0.52) | KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL17018550 | 0.81 | KCNA5 (0.52) | KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL17018553 | 0.81 | KCNA5 (0.52) | KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL12578890 | 0.81 | KCNA5 (0.49) | KCNA5POLBATMLMNAKDM4A | |
| SCHEMBL17018470 | 0.81 | KCNA5 (0.52) | KCNA5KDM4AHDAC10HDAC6 | |
| SCHEMBL6187411 | 0.80 | FDFT1 (0.40) | KCNA5POLBMAPK1ATMKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |