Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31443473 | 1.00 | MEN1 (0.35) | MEN1KMT2ANR1H4MMP2MMP13 | |
| SCHEMBL31443518 | 0.93 | MAPK1 (0.36) | MEN1KMT2ANR1H4MMP2MMP13 | |
| SCHEMBL31443496 | 0.93 | MAPK1 (0.36) | MEN1KMT2ANR1H4MMP2MMP13 | |
| SCHEMBL31443697 | 0.91 | SCN9A (0.41) | SCN9ANR1H2NR1H3ALDH1A1BCL2 | |
| SCHEMBL31443472 | 0.90 | SCN9A (0.39) | SCN9AMAPK1NR1H2NR1H3 | |
| SCHEMBL31443523 | 0.90 | SCN9A (0.39) | SCN9AMAPK1NR1H2NR1H3 | |
| SCHEMBL31443512 | 0.89 | SCN9A (0.34) | MEN1KMT2ANR1H4MMP2MMP13 | |
| SCHEMBL31443607 | 0.89 | SCN9A (0.34) | MEN1KMT2ANR1H4MMP2MMP13 | |
| SCHEMBL31443784 | 0.86 | MAPK1 (0.38) | MAPK1ALDH1A1KCNK3 | |
| SCHEMBL31443553 | 0.85 | NR1H2 (0.32) | NR1H4SCN9AMAPK1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072451-A1 | RAS-PI3K INHIBITORS FOR THE TREATMENT OF CANCER AND IMMUNOLOGICAL DISEASES | VIVIDION THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |