Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 16/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 16/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30389150 | 0.88 | DDB1 (0.50) | DDB1CRBN | |
| SCHEMBL30498612 | 0.87 | DDB1 (0.50) | DDB1CRBNNPC1LMNANR2F2 | |
| SCHEMBL30662928 | 0.87 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL24754836 | 0.87 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL30030025 | 0.87 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL31236477 | 0.87 | DDB1 (0.69) | DDB1CRBNNPC1HTT | |
| SCHEMBL31236481 | 0.87 | DDB1 (0.69) | DDB1CRBNNPC1HTT | |
| SCHEMBL24141401 | 0.86 | DDB1 (0.55) | DDB1CRBN | |
| SCHEMBL24141422 | 0.86 | DDB1 (0.57) | DDB1CRBNLMNA | |
| SCHEMBL30662993 | 0.86 | DDB1 (0.56) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096710-A1 | MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |
| WO-2025096771-A1 | MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |