SCHEMBL31447643

SCHEMBL31447643

O=C1CCC(Nc2ccc(N3CCC(CN4CCNCC4)CC3)c(F)c2)C(=O)N1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.54
CRBN Q96SW2 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30905890 1.00 DDB1 (0.54) DDB1CRBN
SCHEMBL31702534 0.93 DDB1 (0.54) DDB1CRBN
SCHEMBL31701273 0.93 DDB1 (0.54) DDB1CRBN
SCHEMBL30741189 0.93 DDB1 (0.54) DDB1CRBN
SCHEMBL27162987 0.93 DDB1 (0.54) DDB1CRBN
SCHEMBL31333703 0.90 DDB1 (0.47) DDB1CRBN
SCHEMBL25024305 0.89 DDB1 (0.67) DDB1CRBN
SCHEMBL25229880 0.89 DDB1 (0.67) DDB1CRBN
SCHEMBL30981342 0.89 DDB1 (0.67) DDB1CRBN
SCHEMBL25224278 0.89 DDB1 (0.67) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 US claimed
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF BTK, LYN, SYK DDB1 1245/4885CRBN 324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.