SCHEMBL31447868

SCHEMBL31447868

O=C1CCC(Nc2cccc(C(=O)N3CCN(CC4CCNCC4)CC3)c2)C(=O)N1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 16/20 0.51
▸ CRBN Q96SW2 16/20 0.51
▸ EPHX2 P34913 1/20 0.43
▸ CACNA2D1 P54289 1/20 0.42
▸ CACNA1B Q00975 1/20 0.42
▸ CACNB1 Q02641 1/20 0.42
▸ GABRD O14764 1/20 0.41
▸ GABRA1 P14867 1/20 0.41
▸ GABRB1 P18505 1/20 0.41
▸ GABRA5 P31644 1/20 0.41
▸ GABRA3 P34903 1/20 0.41
▸ GABRA2 P47869 1/20 0.41
▸ GABRB2 P47870 1/20 0.41
▸ GABRA4 P48169 1/20 0.41
▸ PARP1 P09874 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31447911 0.94 DDB1 (0.50) DDB1CRBNEPHX2GABRDGABRA1
SCHEMBL30434438 0.92 DDB1 (0.52) DDB1CRBNPARP1
SCHEMBL31447844 0.90 DDB1 (0.50) DDB1CRBNEPHX2
SCHEMBL31447721 0.90 DDB1 (0.56) DDB1CRBNPARP1
SCHEMBL31447845 0.89 DDB1 (0.61) DDB1CRBNPARP1
SCHEMBL31447885 0.85 DDB1 (0.61) DDB1CRBN
SCHEMBL31230812 0.84 DDB1 (0.59) DDB1CRBN
SCHEMBL31230805 0.84 DDB1 (0.59) DDB1CRBN
SCHEMBL30525400 0.84 DDB1 (0.59) DDB1CRBN
SCHEMBL25631852 0.84 DDB1 (0.59) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 — — US claimed
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF BTK, LYN, SYK DDB1 1245/4885CRBN 324/4885EPHX2 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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