SCHEMBL31447951

SCHEMBL31447951

O=C1CCC(N2C(=O)c3cc(F)c(N4CC(CN5CCNCC5)C4)cc3C2=O)C(=O)N1

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 16/20 0.63
▸ DDB1 Q16531 8/20 0.49
▸ IKZF3 Q9UKT9 2/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ CHRM2 P08172 1/20 0.45
▸ OPRM1 P35372 1/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ TNF P01375 1/20 0.44
▸ AR P10275 1/20 0.43
▸ ALK Q9UM73 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31447949 0.92 CRBN (0.66) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL29260269 0.90 CRBN (0.62) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL23173202 0.89 CRBN (0.68) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31605515 0.89 CRBN (0.68) CRBNDDB1IKZF3ALDH1A1CHRM2
Hydrochloric Acid SCHEMBL29710636 0.88 CRBN (0.67) CRBNDDB1IKZF3ALDH1A1CHRM2
Hydrochloric Acid SCHEMBL29096736 0.88 CRBN (0.67) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL20046192 0.87 CRBN (0.78) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL29597287 0.87 CRBN (0.78) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL24735327 0.87 CRBN (0.78) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL29841603 0.87 CRBN (0.78) CRBNDDB1IKZF3ALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 — — US claimed
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF BTK, LYN, SYK CRBN 324/4885DDB1 1245/4885IKZF3 167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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