Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.50 |
| ▸ | REN | P00797 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PEPD | P12955 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | XPNPEP2 | O43895 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378326 | 0.95 | ACE (0.55) | ACERENKDM4EF2LMNA | |
| SCHEMBL7378318 | 0.95 | ACE (0.55) | ACERENKDM4EF2LMNA | |
| Hydrochloric Acid SCHEMBL6338692 | 0.93 | ACE (0.54) | ACERENKDM4EF2LMNA | |
| SCHEMBL10657872 | 0.82 | ACE (0.48) | ACERENKDM4EF2LMNA | |
| Hydrochloric Acid SCHEMBL11337063 | 0.81 | DPP4 (0.46) | ACERENKDM4EF2LMNA | |
| SCHEMBL10654681 | 0.81 | PREP (0.57) | ACERENKDM4EF2LMNA | |
| SCHEMBL6779161 | 0.81 | PEPD (0.47) | KDM4ELMNAPEPDDPP4 | |
| Hydrochloric Acid SCHEMBL6563446 | 0.80 | PEPD (0.46) | KDM4ELMNAPEPDDPP4 | |
| SCHEMBL29384148 | 0.78 | ACE (0.49) | ACERENKDM4EF2LMNA | |
| SCHEMBL10658127 | 0.78 | ACE (0.56) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119522235-A | VEGF-C muteins for selective lymphatic stimulation | 耶鲁大学 | 2025-02-25 | — | — | CN | disclosed |