Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 5/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34473824 | 1.00 | JAK3 (0.42) | JAK3GRIN2BGRIN2CNAMPTSOS1 | |
| SCHEMBL1771960 | 1.00 | JAK3 (0.42) | JAK3GRIN2BGRIN2CNAMPTSOS1 | |
| SCHEMBL1555738 | 0.96 | JAK3 (0.44) | JAK3GRIN2BGRIN2CNAMPTSOS1 | |
| SCHEMBL1947698 | 0.94 | JAK3 (0.42) | JAK3GRIN2BGRIN2CNAMPTSOS1 | |
| SCHEMBL24491096 | 0.91 | JAK3 (0.37) | JAK3GRIN2BGRIN2CNAMPTSOS1 | |
| SCHEMBL26848595 | 0.91 | JAK3 (0.37) | JAK3GRIN2BGRIN2CNAMPTSOS1 | |
| SCHEMBL700241 | 0.91 | JAK3 (0.43) | JAK3GRIN2BGRIN2CNAMPTSPR | |
| SCHEMBL16528900 | 0.90 | JAK3 (0.44) | JAK3GRIN2BGRIN2CNAMPTSOS1 | |
| SCHEMBL10277023 | 0.90 | SOS1 (0.45) | JAK3GRIN2BGRIN2CSOS1SOS2 | |
| SCHEMBL22169129 | 0.90 | SOS1 (0.41) | JAK3GRIN2BGRIN2CSOS1SOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743464-A1 | SOMATOSTATIN SUBTYPE RECEPTOR 3 (SSTR3) AGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025019256-A1 | SOMATOSTATIN SUBTYPE RECEPTOR 3 (SSTR3) AGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2025-01-23 | — | — | WO | disclosed |