Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 20/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.81 |
| ▸ | PLK1 | P53350 | 1/20 | 0.81 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.81 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.81 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482704 | 1.00 | WEE1 (1.00) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL21333309 | 1.00 | WEE1 (1.00) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL21332688 | 1.00 | WEE1 (1.00) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL21332940 | 1.00 | WEE1 (1.00) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL21333282 | 0.94 | WEE1 (0.88) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL31613787 | 0.94 | WEE1 (0.88) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL29482710 | 0.94 | WEE1 (0.88) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL21332682 | 0.94 | WEE1 (0.88) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL21332681 | 0.94 | WEE1 (0.88) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25060979 | 0.93 | WEE1 (0.87) | WEE1EGFRCYP3A4PLK1MAP3K19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4566612-A2 | SUBSTITUTED 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES | Recurium IP Holdings, LLC (US) | 2025-06-11 | — | — | EP | disclosed |
| EP-3762385-B1 | SUBSTITUTED 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES | RECURIUM IP HOLDINGS LLC (US) | 2025-02-12 | — | — | EP | disclosed |