Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 14/20 | 0.89 |
| ▸ | BCL2 | P10415 | 9/20 | 0.86 |
| ▸ | MDM4 | O15151 | 1/20 | 0.86 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.86 |
| ▸ | TP53 | P04637 | 1/20 | 0.86 |
| ▸ | BID | P55957 | 1/20 | 0.86 |
| ▸ | BAX | Q07812 | 1/20 | 0.86 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.86 |
| ▸ | ASPH | Q12797 | 1/20 | 0.86 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.86 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.86 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.86 |
| ▸ | BAD | Q92934 | 1/20 | 0.86 |
| ▸ | BBC3 | Q9BXH1 | 1/20 | 0.86 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.81 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.81 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.81 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.81 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.81 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26648036 | 1.00 | BCL2L1 (0.89) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540092 | 1.00 | BCL2L1 (0.89) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1541027 | 0.95 | BCL2L1 (0.88) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540102 | 0.94 | BCL2L1 (0.91) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540891 | 0.94 | BCL2L1 (0.86) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1541081 | 0.93 | BCL2L1 (0.85) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540155 | 0.93 | BCL2L1 (0.89) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540259 | 0.93 | BCL2L1 (0.87) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL3715789 | 0.93 | BCL2L1 (0.91) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1541440 | 0.93 | BCL2L1 (0.91) | BCL2L1BCL2MDM4BCL2L11TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522154-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |