Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 17/20 | 0.75 |
| ▸ | BCL2L1 | Q07817 | 14/20 | 0.75 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.61 |
| ▸ | BAD | Q92934 | 2/20 | 0.61 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | ASPH | Q12797 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26647951 | 0.90 | BCL2L1 (0.86) | BCL2BCL2L1BCL2L2BADBCL2L11 | |
| SCHEMBL25603128 | 0.89 | BCL2 (0.81) | BCL2BCL2L1BCL2L2BADBCL2L11 | |
| SCHEMBL25603135 | 0.88 | BCL2L1 (0.81) | BCL2BCL2L1BCL2L2BADBCL2L11 | |
| SCHEMBL19014716 | 0.88 | BCL2 (0.84) | BCL2BCL2L1BCL2L2BADBCL2L11 | |
| SCHEMBL19425135 | 0.83 | BCL2 (0.77) | BCL2BCL2L1BCL2L2BADBCL2L11 | |
| SCHEMBL20305898 | 0.83 | BCL2 (1.00) | BCL2BCL2L1BCL2L2BADBCL2L11 | |
| SCHEMBL19425407 | 0.82 | BCL2 (0.76) | BCL2BCL2L1BCL2L2BADBCL2L11 | |
| SCHEMBL22295609 | 0.82 | BCL2L1 (0.76) | BCL2BCL2L1BCL2L2BADBCL2L11 | |
| SCHEMBL30281724 | 0.81 | BCL2L1 (0.83) | BCL2BCL2L1BCL2L2BADBCL2L11 | |
| SCHEMBL25600935 | 0.81 | BCL2 (0.80) | BCL2BCL2L1BCL2L2BADBCL2L11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522154-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |