Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 9/20 | 0.66 |
| ▸ | MAPT | P10636 | 8/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31451702 | 0.95 | MAPT (0.69) | TP53MAPTKMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL31451268 | 0.90 | MAPT (0.67) | TP53MAPTKMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL31451654 | 0.89 | MAPT (0.69) | TP53MAPTKMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL31451514 | 0.88 | MAPT (0.69) | TP53MAPTKMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL31451710 | 0.83 | MAPT (0.66) | TP53MAPTKMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL31451632 | 0.82 | TP53 (0.57) | TP53MAPTKMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL31451507 | 0.82 | MAPT (0.64) | TP53MAPTKMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL31451567 | 0.81 | MAPT (0.60) | TP53MAPTKMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL31451577 | 0.80 | MAPT (0.70) | TP53MAPTKMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL31451534 | 0.80 | MAPT (0.70) | TP53MAPTKMT2ARXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054187-A1 | TGR5 ANTAGONISTS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2025-03-13 | — | — | WO | disclosed |