Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 18/20 | 0.65 |
| ▸ | MC3R | P41968 | 8/20 | 0.64 |
| ▸ | MC1R | Q01726 | 8/20 | 0.64 |
| ▸ | MC5R | P33032 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156665 | 0.94 | MC4R (0.68) | MC4RMC3RMC1RMC5RALDH1A1 | |
| SCHEMBL3156125 | 0.92 | MC4R (0.68) | MC4RMC3RMC1RMC5RALDH1A1 | |
| SCHEMBL3147970 | 0.91 | MC4R (0.68) | MC4RMC3RMC1RMC5RALDH1A1 | |
| SCHEMBL3151159 | 0.89 | MC4R (0.68) | MC4RMC3RMC1RMC5RALDH1A1 | |
| SCHEMBL3148275 | 0.89 | MC4R (0.68) | MC4RMC3RMC1RMC5RALDH1A1 | |
| SCHEMBL3148268 | 0.89 | MC4R (0.68) | MC4RMC3RMC1RMC5RALDH1A1 | |
| SCHEMBL3143486 | 0.88 | MC4R (0.78) | MC4RMC3RMC1RMC5RALDH1A1 | |
| SCHEMBL3153936 | 0.87 | MC4R (0.70) | MC4RMC3RMC1RMC5RALDH1A1 | |
| SCHEMBL3148202 | 0.87 | MC4R (0.72) | MC4RMC3RMC1RMC5RALDH1A1 | |
| SCHEMBL3142002 | 0.87 | MC4R (0.74) | MC4RMC3RMC1RMC5RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773796-B1 | OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2010-03-03 | — | — | EP | claimed |