Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31451730 | 0.97 | KRAS (0.43) | KRASSOS1 | |
| SCHEMBL31451475 | 0.91 | KRAS (0.46) | KRAS | |
| SCHEMBL31451758 | 0.91 | KRAS (0.44) | KRASSOS1 | |
| SCHEMBL31451787 | 0.91 | KRAS (0.45) | KRAS | |
| SCHEMBL31451740 | 0.91 | KRAS (0.38) | KRASSOS1 | |
| SCHEMBL31451734 | 0.90 | KRAS (0.45) | KRASSOS1 | |
| SCHEMBL31451673 | 0.90 | KRAS (0.43) | KRASSOS1 | |
| SCHEMBL31451742 | 0.90 | KRAS (0.45) | KRAS | |
| SCHEMBL31451771 | 0.88 | KRAS (0.53) | KRAS | |
| SCHEMBL31451622 | 0.86 | KRAS (0.42) | KRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016899-A1 | SPIROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2025-01-23 | — | — | WO | claimed |
| WO-2025016899-A1 | SPIROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2025-01-23 | — | — | WO | disclosed |