Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.72 |
| ▸ | CCR3 | P51677 | 4/20 | 0.72 |
| ▸ | DRD4 | P21917 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144416 | 0.91 | MCHR1 (0.67) | MCHR1CCR3DRD4 | |
| SCHEMBL3135668 | 0.88 | MCHR1 (0.66) | MCHR1CCR3DRD4 | |
| SCHEMBL3144093 | 0.88 | MCHR1 (0.69) | MCHR1CCR3DRD4 | |
| SCHEMBL3145038 | 0.85 | MCHR1 (0.62) | MCHR1CCR3DRD4 | |
| SCHEMBL3134114 | 0.84 | MCHR1 (0.90) | MCHR1CCR3DRD4 | |
| SCHEMBL14290645 | 0.84 | DRD4 (0.61) | MCHR1CCR3DRD4 | |
| SCHEMBL3153217 | 0.83 | MCHR1 (0.90) | MCHR1CCR3DRD4 | |
| SCHEMBL14291138 | 0.81 | DRD4 (0.57) | MCHR1CCR3DRD4 | |
| SCHEMBL3141238 | 0.81 | MCHR1 (0.64) | MCHR1CCR3DRD4 | |
| SCHEMBL13991076 | 0.80 | MCHR1 (1.00) | MCHR1CCR3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081825-A1 | 1-NAPHTHYL ALKYLPIPERIDINE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2010-04-01 | — | — | US | disclosed |
| EP-2098509-A1 | 1-NAPHTHYL ALKYLPIPERIDINE DERIVATIVE | Taisho Pharmaceutical Co. Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081825-A1 | 1-NAPHTHYL ALKYLPIPERIDINE DERIVATIVE | MCHR1, MCHR2, MC5R | MCHR1 1/4885CCR3 4143/4885DRD4 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.