Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | UBE2N | P61088 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | PGK1 | P00558 | 2/20 | 0.57 |
| ▸ | KMT5A | Q9NQR1 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | WHR1 | P49842 | 2/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31453016 | 0.86 | TLR9 (0.60) | TLR9POLBHPGDUBE2NTDP1 | |
| SCHEMBL3972349 | 0.85 | TLR9 (0.66) | TLR9POLBHPGDUBE2NTDP1 | |
| SCHEMBL29360163 | 0.84 | TLR9 (1.00) | TLR9CYP1A2CYP3A4CYP2D6CLK4 | |
| SCHEMBL12175518 | 0.84 | TLR9 (1.00) | TLR9CYP1A2CYP3A4CYP2D6CLK4 | |
| SCHEMBL31453014 | 0.81 | HTT (0.65) | TLR9PGK1KMT5AKDM1AEHMT2 | |
| SCHEMBL1084058 | 0.80 | CYP1A2 (0.65) | TLR9POLBHPGDCYP1A2CYP3A4 | |
| SCHEMBL31453013 | 0.80 | TLR9 (0.57) | TLR9POLBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31612806 | 0.78 | CYP1A2 (0.66) | TLR9POLBTDP1CYP1A2CYP3A4 | |
| SCHEMBL1085578 | 0.78 | CYP1A2 (0.79) | TLR9POLBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14233119 | 0.77 | TLR9 (0.64) | TLR9USP2HSD17B10ACP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751364-A | Dimethoxy quinazoline compound and application thereof | 中日友好医院(中日友好临床医学研究所) | 2025-04-04 | — | — | CN | disclosed |