SCHEMBL3145349

SCHEMBL3145349

CCCCON1C(=O)c2cccc3c(OC)ccc(c23)C1=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.67
PRMT1 Q99873 1/20 0.60
KMT2A Q03164 6/20 0.59
MAPT P10636 4/20 0.59
LMNA P02545 4/20 0.59
ALDH1A1 P00352 4/20 0.59
KDM4E B2RXH2 4/20 0.59
POLB P06746 3/20 0.59
HTT P42858 3/20 0.59
PABPC1 P11940 1/20 0.59
XBP1 P17861 1/20 0.59
NFKB1 P19838 1/20 0.59
SMARCA2 P51531 1/20 0.59
NFKB2 Q00653 1/20 0.59
RELA Q04206 1/20 0.59
RECQL P46063 2/20 0.50
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9437170 0.82 PRMT1 (0.68) TDP1PRMT1KMT2AMAPTLMNA
SCHEMBL30534976 0.82 PRMT1 (0.68) TDP1PRMT1KMT2AMAPTLMNA
SCHEMBL11718139 0.81 PRMT1 (0.59) TDP1PRMT1KMT2AMAPTLMNA
SCHEMBL13495346 0.81 PRMT1 (0.74) PRMT1KMT2AMAPTLMNAALDH1A1
SCHEMBL28735834 0.81 PRMT1 (0.74) PRMT1KMT2AMAPTLMNAALDH1A1
SCHEMBL11779606 0.80 TDP1 (0.56) TDP1PRMT1KMT2AMAPTLMNA
SCHEMBL11780905 0.80 TDP1 (0.56) TDP1PRMT1KMT2AMAPTLMNA
SCHEMBL28763092 0.80 TDP1 (0.63) TDP1PRMT1KMT2AMAPTLMNA
SCHEMBL7706791 0.80 PRMT1 (0.60) PRMT1KMT2AMAPTLMNAALDH1A1
SCHEMBL9437172 0.79 PRMT1 (0.71) TDP1PRMT1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7641765-B2 Applying slurry containing optical brighteners BASF AKTIENGESELLSCHAFT (DE) 2010-01-05 US disclosed
EP-1438197-B1 METHOD FOR INCREASING THE WHITENESS OF PAPER BY MEANS OF CATIONIC POLYELECTROLYTES BASF SE (DE) 2008-10-15 EP disclosed
EP-1419298-B8 METHOD FOR PRODUCTION OF COATED PAPER WITH EXTREME WHITENESS BASF SE (DE) 2008-04-02 EP disclosed
EP-1419298-B1 METHOD FOR PRODUCTION OF COATED PAPER WITH EXTREME WHITENESS BASF AG (DE) 2008-02-13 EP disclosed
US-20050061461-A1 Production of paper board and cardboard BASF AKTIENGESELLSCHAFT (DE) 2005-03-24 US disclosed
US-20040238791-A1 Reinforcement of the effect of optical brighteners by means of polymers BASF AKTIENGESELLSCHAFT (DE) 2004-12-02 US disclosed
US-20040182533-A1 Method for increasing the whiteness of paper by means of cationic polyelectrolytes BASF SE (DE) 2004-09-23 US disclosed
EP-1458933-A1 METHOD FOR PRODUCING PAPER, PAPERBOARD AND CARDBOARD BASF AKTIENGESELLSCHAFT (DE) 2004-09-22 EP disclosed
EP-1448690-A1 REINFORCEMENT OF THE EFFECT OF OPTICAL BRIGHTENERS BY MEANS OF POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2004-08-25 EP disclosed
US-20040154764-A1 Applying slurry containing optical brighteners BASF AKTIENGESELLSCHAFT (DE) 2004-08-12 US disclosed
EP-1438197-A2 METHOD FOR INCREASING THE WHITENESS OF PAPER BY MEANS OF CATIONIC POLYELECTROLYTES BASF AKTIENGESELLSCHAFT (DE) 2004-07-21 EP disclosed
EP-1419298-A1 METHOD FOR PRODUCTION OF COATED PAPER WITH EXTREME WHITENESS BASF AKTIENGESELLSCHAFT (DE) 2004-05-19 EP disclosed
WO-2003052205-A1 METHOD FOR PRODUCING PAPER, PAPERBOARD AND CARDBOARD BASF AKTIENGESELLSCHAFT (DE) 2003-06-26 WO disclosed
WO-2003022924-A1 POLYMER DISPERSIONS COMPRISING VINYLAMIDE COPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 2003-03-20 WO disclosed
WO-2003020808-A1 REINFORCEMENT OF THE EFFECT OF OPTICAL BRIGHTENERS BY MEANS OF POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2003-03-13 WO disclosed
WO-2003021041-A2 METHOD FOR INCREASING THE WHITENESS OF PAPER BY MEANS OF CATIONIC POLYELECTROLYTES BASF AKTIENGESELLSCHAFT (DE) 2003-03-13 WO disclosed
WO-2003016624-A1 METHOD FOR PRODUCTION OF COATED PAPER WITH EXTREME WHITENESS BASF AKTIENGESELLSCHAFT (DE) 2003-02-27 WO disclosed