Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 11/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455029 | 0.93 | AKT1 (0.43) | AKT1ABL1BRAFKDRAKT2 | |
| SCHEMBL31455286 | 0.89 | ABL1 (0.45) | AKT1ABL1AKT2AKT3 | |
| SCHEMBL31455166 | 0.86 | AKT1 (0.50) | AKT1ABL1AKT2GSK3BAKT3 | |
| SCHEMBL31454982 | 0.86 | AKT1 (0.45) | AKT1ABL1AKT2AKT3 | |
| SCHEMBL31455633 | 0.85 | AKT1 (0.46) | AKT1AKT2AKT3 | |
| SCHEMBL31455906 | 0.83 | AKT1 (0.43) | AKT1ABL1AKT2AKT3 | |
| SCHEMBL31455139 | 0.83 | AKT1 (0.50) | AKT1ABL1AKT2AKT3 | |
| SCHEMBL31455431 | 0.82 | ABL1 (0.45) | AKT1ABL1AKT2GSK3BAKT3 | |
| SCHEMBL31455130 | 0.81 | AKT1 (0.48) | AKT1ABL1AKT2GSK3BAKT3 | |
| SCHEMBL31455380 | 0.80 | AKT1 (0.49) | AKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |