Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14225756 | 0.89 | PDE4B (0.53) | PDE4BHDAC1HDAC2USP30MEN1 | |
| SCHEMBL21381911 | 0.88 | PDE4B (0.49) | PDE4BRORCKDM4ENR1H2NAMPT | |
| SCHEMBL30149865 | 0.88 | PDE4B (0.49) | PDE4BRORCKDM4ENR1H2NAMPT | |
| SCHEMBL12479918 | 0.87 | NAMPT (0.52) | PDE4BKDM4ENAMPTKMT2A | |
| SCHEMBL15174834 | 0.86 | PDE4B (0.46) | PDE4BHDAC1HDAC2RORCKDM4E | |
| SCHEMBL15173613 | 0.86 | HDAC1 (0.49) | PDE4BHDAC1HDAC2RORCKDM4E | |
| SCHEMBL24583221 | 0.85 | PDE4B (0.47) | PDE4BRORCKDM4ENR1H2NAMPT | |
| SCHEMBL15173515 | 0.85 | PDE4B (0.45) | PDE4BHDAC1HDAC2RORCKDM4E | |
| SCHEMBL30273467 | 0.84 | HDAC2 (0.50) | PDE4BHDAC1HDAC2RORCKDM4E | |
| SCHEMBL25036969 | 0.84 | HDAC2 (0.50) | PDE4BHDAC1HDAC2RORCKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |