Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 19/20 | 0.48 |
| ▸ | AKT2 | P31751 | 14/20 | 0.48 |
| ▸ | AKT3 | Q9Y243 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31420267 | 0.83 | AKT1 (0.69) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL31455083 | 0.81 | AKT1 (0.73) | AKT1AKT2AKT3CYP1A2CYP3A4 | |
| SCHEMBL31455193 | 0.80 | AKT1 (0.46) | AKT1AKT2AKT3CYP1A2CYP3A4 | |
| SCHEMBL31455166 | 0.80 | AKT1 (0.50) | AKT1AKT2AKT3 | |
| SCHEMBL31455152 | 0.79 | AKT1 (0.44) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL31455139 | 0.78 | AKT1 (0.50) | AKT1AKT2AKT3CYP1A2CYP3A4 | |
| SCHEMBL31455130 | 0.77 | AKT1 (0.48) | AKT1AKT2AKT3CYP2C8CYP2D6 | |
| SCHEMBL31455380 | 0.77 | AKT1 (0.49) | AKT1AKT2AKT3CYP1A2CYP3A4 | |
| SCHEMBL31455097 | 0.75 | AKT1 (0.55) | AKT1AKT2AKT3CYP2C8CYP2D6 | |
| SCHEMBL30815520 | 0.71 | AKT1 (0.50) | AKT1AKT2AKT3CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |