Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.46 |
| ▸ | AKT2 | P31751 | 10/20 | 0.46 |
| ▸ | AKT3 | Q9Y243 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455068 | 1.00 | AKT1 (0.46) | AKT1AKT2AKT3 | |
| SCHEMBL31455125 | 0.93 | AKT1 (0.45) | AKT1AKT2AKT3 | |
| SCHEMBL31455281 | 0.93 | AKT1 (0.45) | AKT1AKT2AKT3 | |
| SCHEMBL31455666 | 0.88 | AKT1 (0.57) | AKT1AKT2AKT3 | |
| SCHEMBL31455484 | 0.88 | AKT1 (0.57) | AKT1AKT2AKT3 | |
| SCHEMBL31454985 | 0.87 | AKT1 (0.58) | AKT1AKT2AKT3 | |
| SCHEMBL31454981 | 0.87 | AKT1 (0.58) | AKT1AKT2AKT3 | |
| SCHEMBL31455228 | 0.85 | AKT1 (0.59) | AKT1AKT2AKT3 | |
| SCHEMBL31455367 | 0.85 | AKT1 (0.59) | AKT1AKT2AKT3 | |
| SCHEMBL31455245 | 0.84 | AKT1 (0.42) | AKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |