Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1418414 | 0.91 | PDGFRB (0.42) | NOTUMKDM4EHPGDALDH1A1GAA | |
| SCHEMBL4101519 | 0.87 | KDM4E (0.44) | NOTUMKDM4EHPGDALDH1A1GAA | |
| SCHEMBL30182718 | 0.87 | KDM4E (0.44) | NOTUMKDM4EHPGDALDH1A1GAA | |
| SCHEMBL19993672 | 0.85 | MAPT (0.42) | NOTUMKDM4EHPGDALDH1A1GAA | |
| SCHEMBL1418105 | 0.85 | KDM4E (0.44) | NOTUMKDM4EHPGDALDH1A1GAA | |
| SCHEMBL522786 | 0.84 | CA12 (0.47) | KDM4EHPGDALDH1A1GAAMAPT | |
| SCHEMBL14186809 | 0.83 | MAPT (0.41) | KDM4EHPGDALDH1A1GAAMAPT | |
| SCHEMBL365903 | 0.83 | MAPT (0.41) | KDM4EHPGDALDH1A1GAAMAPT | |
| SCHEMBL27890 | 0.81 | KDM4E (0.43) | NOTUMKDM4EHPGDALDH1A1GAA | |
| SCHEMBL15544006 | 0.81 | KDM4E (0.43) | NOTUMKDM4EHPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |