SCHEMBL31455701

SCHEMBL31455701

CC(C)c1ccc2nc(-c3cccnc3N)n(-c3ccc(C4CN(C(=O)OC(C)(C)C)C4)cc3)c2n1

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 20/20 0.48
AKT2 P31751 5/20 0.48
AKT3 Q9Y243 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31455812 0.87 AKT1 (0.48) AKT1AKT2AKT3
SCHEMBL31420347 0.87 AKT1 (0.62) AKT1AKT2AKT3
SCHEMBL31455076 0.85 AKT1 (0.53) AKT1AKT2AKT3
SCHEMBL31455358 0.82 AKT1 (0.47) AKT1AKT2AKT3
SCHEMBL31455216 0.82 AKT1 (0.42) AKT1AKT2AKT3
SCHEMBL31455354 0.81 AKT1 (0.59) AKT1AKT2AKT3
SCHEMBL31455236 0.81 AKT1 (0.43) AKT1AKT2AKT3
SCHEMBL31455817 0.81 AKT1 (0.53) AKT1AKT2AKT3
SCHEMBL31455291 0.81 AKT1 (0.58) AKT1AKT2AKT3
SCHEMBL31455468 0.81 AKT1 (0.44) AKT1AKT2AKT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059562-A1 SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME ATAVISTIK BIO, INC. (US) 2025-03-20 WO disclosed