SCHEMBL31455772

SCHEMBL31455772

CC(C)(C)OC(=O)NCc1ccc(-n2c(-c3cccnc3N)nc3cc(C(N)=O)cnc32)cc1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 20/20 0.60
AKT2 P31751 13/20 0.60
AKT3 Q9Y243 7/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31455839 0.94 AKT1 (0.63) AKT1AKT2AKT3
SCHEMBL31455918 0.93 AKT1 (0.60) AKT1AKT2AKT3
SCHEMBL2178315 0.91 AKT1 (0.66) AKT1AKT2AKT3
SCHEMBL30574882 0.90 AKT1 (0.61) AKT1AKT2AKT3
SCHEMBL2174457 0.90 AKT1 (0.73) AKT1AKT2AKT3
SCHEMBL30815468 0.90 AKT1 (0.73) AKT1AKT2AKT3
SCHEMBL30574785 0.88 AKT1 (0.76) AKT1AKT2AKT3
SCHEMBL2176493 0.88 AKT1 (0.76) AKT1AKT2AKT3
SCHEMBL31455872 0.88 AKT1 (0.59) AKT1AKT2AKT3
SCHEMBL30814990 0.88 AKT1 (0.76) AKT1AKT2AKT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059562-A1 SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME ATAVISTIK BIO, INC. (US) 2025-03-20 WO disclosed